I you want to know why I was so prolific it was I had one glorious day on the Classic version of Blogger. Now I am FORCED to use the new “improved” version where everything takes 2-3 times as long.
I rate this edition of Tru News, so will be bringing the material when I can.
CHINESE WHISTLEBLOWER: ASK DR. FAUCI! HE KNOWS A LOT ABOUT CHINESE VIRUS RESEARCH
Today on TruNews we discuss the war-starting statements by Hong Kong virologist Dr. Li-Meng Yan, concerning the nefarious origins of the coronavirus. She details that the Chinese military not only weaponized the virus, but intentionally deployed it to kill their enemies in the West. We also share China’s response, including a threat against Taiwan and U.S. aircraft carriers.
Rick Wiles, Doc Burkhart, Edward Szall. Airdate 09/17/2020
Watch broadcast HERE
U.S. intelligence agencies recently increased their knowledge of China’s covert biological weapons program with the help of a defector from the People’s Liberation Army, according to people familiar with the incident.
The defector escaped from China and traveled to Europe, where he is under the protection of a European government security service, according to the sources. The PLA defector believes that Chinese intelligence has penetrated the U.S. government and is therefore wary of cooperating with the CIA and other Western spy agencies.
Still, the defector has provided some information about China’s biological arms program that has reached the U.S. government. No other details of the defection could be learned.
However, the defector is the second person from China to provide information about Chinese biological research with potential weapons applications.
https://www.washingtontimes.com/news/2020/sep/16/second-china-defector-gives-biological-weapons-inf/
New Delhi: A former Chinese virologist from Hong Kong Dr Li-Meng Yan has claimed that the SARS-CoV-2 virus was developed in a government laboratory in Wuhan and also said that she has evidence to back the claim, in an interview with UK channel ITV.
In the channel’s ‘Loose Women’ segment, Li-Meng maintained that the virus is a “highly mutant” one and that the Wuhan seafood market and the other intermediate hosts of the virus were just a “smokescreen”.
In the latest interview, when asked for her take on negotiations between China and the WHO regarding its investigation into the origin of the coronavirus pandemic, Yan said the two parties will first hold backdoor discussions on the "benefits" for the WHO and the Chinese Communist Party (CCP) government. She alleged that after the "benefits" are agreed upon, the two parties will sit down and decide "what to tell the people, whether this is really from some bats, even the 'one belt one road' countries, or some poor animals they suddenly caught in Wuhan."
Yan then claimed that she and her team have produced a scientific report that shows the origin of COVID-19 is the "PLA-owned Zhoushan bat coronavirus." She plans to release the report in the near future, and accuses the WHO of "covering up numerous lies for the CCP."
She pointed out that at the end of February, the WHO sent experts, including the controversial Bruce Aylward, who later published a report that praised the Chinese government's handling of the outbreak. However, she claims the WHO "dared not admit Shi Zhengli's RaTG13 virus."
The virologist said Wuhan Institute of Virology (WIV) scientist Shi Zhengli, also known as "Bat Woman," deliberately posted a paper on Feb. 3 to draw attention to a coronavirus strain identified as RaTG13, which is a strain she and her team discovered in bats in Yunnan in 2013 and that is 96 percent identical to SARS-CoV-2. Yan claims this was an orchestrated attempt to throw investigators off the Zhoushan bat virus strains, while Shi herself claims the fact that RaTG13 is 4 percent different from SARS-CoV-2 exonerates her lab from being the source of the outbreak.
Yan claims the document posted on WHO's website after the visit to Wuhan pointed out the origin of COVID-19 (SARS-CoV-2) is "actually closest to the Zhoushan bat virus." According to Yan, an examination of the genome sequences released by the Chinese government on Jan. 14 also shows that Zhoushan ZC45 and ZXC21 are the closest to SARS-CoV-2 and that they are the "backbone" upon which COVID-19 was constructed.
When asked if the Zhoushan strain is in the PLA's catalog of viruses and if COVID-19 resulted from gain-of-function or other manipulations in the WIV, Yan said the virus could have come from any one of the PLA's numerous labs, such as in Hong Kong, Shanghai, or Harbin. Gain-of-function is when viruses are engineered to become more deadly or transmissible.
Speaking of gain-of-function research, Yan alleged that White House health advisor Dr. Anthony Fauci knows "more than me how they approved those gain-of-function research findings to (fund) these Chinese labs under the CCP's control," possibly in reference to a Newsweek report alleging Fauci's organization funded gain-of-function research on bat coronavirus at the WIV.
In response to the question, do Western scientists prefer to engage in more dangerous research in communist China due to its notoriously lax safety standards? Yan cited the case of Dr. He Jiankui, who performed gene editing on human embryos to supposedly make them immune to HIV. Yan said that although such controversial experiments would never be allowed in Western countries, the Chinese government feigned ignorance and allowed the experiments to continue.
Indeed, a report by the health website STAT indicates government funding may have been used for He's project. She added that reports have surfaced appearing to show links between a number of American scientists and He's experiments.
She said this was illustrative of how dangerous and ethically questionable scientific experiments can be outsourced to China. Yan claimed that she attended a conference in which He gave a presentation and she questioned him on his research.
Yan said an ethos of making a profit without concern for ethical standards or fear of public health consequences allowed for gain-of-function experiments on coronavirus strains. She lamented the resulting pandemic has severely impacted global health and destroyed the world economy.
When asked if the CCP should be held accountable for the pandemic, Yan said that when she worked on vaccines and virus function testing in Chinese labs and carried out virus replication, "We never made just one type of virus we make a lot of strains of virus and stocked them and then later we would test their function, test their characteristics."
Yan emphasized that COVID-19 is not from nature, but rather it is "lab-modified." The virologist then appeared to indicate that other strains may have been released from PLA labs, which vaccines based on the previous versions would be unable to protect against.
….In August, Yan claimed that she and her team had produced a scientific report that shows the origin of COVID-19 is the "PLA-owned Zhoushan bat coronavirus." She stated that she planned to release the report in the near future, and accused the World Health Organization (WHO) of "covering up numerous lies for the CCP."
On Monday, Yan released the report on the data platform Zenodo with the title "Unusual Features of the SARS-CoV-2 Genome Suggesting Sophisticated Laboratory Modification Rather Than Natural Evolution and Delineation of Its Probable Synthetic Route." Zenodo is a general open access repository developed under the European OpenAIRE project and operated by the European Organization for Nuclear Research (CERN), allowing researchers to store data, software, reports, and any research-related tools.
In the abstract, Yan's team pointed out that despite the fact that COVID-19 (SARS-CoV-2) has claimed the lives of over 900,000 people and devastated the global economy, the origin of the virus remains a mystery and highly controversial. The theory that the virus originated in nature is widely accepted, despite the lack of solid evidence, while suggestions that the disease may have come from a laboratory have been strictly censored from scientific journals, according to the report.
The paper pointed out that the biological characteristics of SARS-CoV-2 are not consistent with a naturally occurring zoonotic virus. The researchers assert that the genomic, structural, medical, and literaty evidence presented in the paper strongly contradicts the natural origin theory.
As previously mentioned by Yan, the researchers claim that evidence provided in the report point to the ZC45 and ZXC21 bat coronaviruses as the model or base for the chimera that became SARS-CoV-2.
Furthermore, the authors postulate that the steps needed to produce the virus synthetically in a laboratory can be achieved in "approximately six months." The scientists then call for an independent investigation into China's virology laboratories, particularly gain-of-function research carried out at the Wuhan Institue of Virology (WIV).
In Part 1 of the paper, the scientists provide evidence that the SARS-CoV-2 was subjected to in vitro manipulation. First, it states that the genomic sequence of the virus is strikingly similar to that of a bat coronavirus found by People's Liberation Army (PLA) labs in the Third Military Medical University in Chongqing, China, and the Research Institute for Medicine of Nanjing Command in Nanjing, China.
Second, it shows that the receptor-binding motif (RBM) found in the virus's notorious spike protein is "suspiciously" similar to SARS-CoV from the 2003 SARS outbreak, indicating it was genetically modified. Third, the spike protein of the virus contains a unique furin cleavage site that is "completely absent in this particular class of coronaviruses found in nature," while the rare codons seen in this sequence suggest that it could have been inserted into the genome artificially
Regarding the "Zhoushan bat virus," the team wrote that ZC45 and ZXC2 have the highest sequence identity with SARS-CoV-2. In terms of similarity between ZC45/ZXC2 and SARS-CoV-2, the genome is 97 percent identical, the nucleocapsid protein is 94 percent identical, the membrane protein is 98.6 percent identical, and the S2 portion (2nd half) of the spike protein is 95 percent identical.
The paper emphasized that the Orf8 protein is 94.2 percent identical, while the E protein is 100 percent identical. The Orf8 is highly unusual in coronaviruses, while no other known coronaviruses share 100 percent of the E protein with SARS-CoV-2 besides ZC45/ZXC2.
The study excludes the RaTG13 virus submitted by WIV scientist Shi Zhengli, also known as "Bat Woman," because recent research has shown that its spike protein cannot bind to the angiotensin-converting enzyme 2 (ACE2) of two types of horseshoe bats, the alleged natural host, indicating that it may be "fabricated to shift the attention away from ZC45/ZXC2.
In Part 2 of the paper, the researches describe how SARS-CoV-2 could be designed and "created conveniently" in laboratories using the ZC45/ZXC2 viruses as the backbone. The scientists postulate that Step 1 consisted of replacing the RBM with a "designed and possibly optimized RBM" using that of SARS-CoV as a guide to enable it to bind with the human angiotensin-converting enzyme 2 (hACE2).
The authors pointed out that Shi, along with long-term partner and structural biology specialist Fang Li, had successfully modified the RBM in this way. The report estimates that this first phase would take about one and a half months.
Step 2 would consist of engineering a furin cleavage site at the S1/S2 junction of the spike protein. According to the researchers, this short stretch of gene sequence can be "conveniently inserted" using a number of standard cloning techniques, such as "QuikChange Site-Directed PCR60, overlap PCR followed by restriction enzyme digestion and ligation91, or Gibson assembly."
The authors stated that none of these methods would leave any trace in the sequence. This further modification of the spike, including the furin-cleavage site, could be completed in "no more than two weeks," according to the report.
Step 3 could be carried out simultaneously with the previous steps and would consist of acquiring an ORF1b gene that holds the RdRpgene segment from RaBtCoV/4991, a bat coronavirus discovered in 2013. The authors believe that that the Chinese virologists wanted the RdRp protein either to ensure that the resulting chimera would be classified in different groups/sub-lineages than ZC45/ZXC2 in phylogenetic studies or to test antiviral drugs.
Step 4 would involve using reverse genetics to produce the chimera and recover live viruses within the course of two weeks. The authors cited an example of how a Swiss team was able to reconstruct the entire SARS-CoV-2 genome using transformation-assisted recombination in yeast within a single week.
Significantly, this method has been available since 2017 and "would not leave any trace of artificial manipulation in the created viral genome." The paper also mentioned that the WIV has used alternative methods of reverse genetics in the past.
Step 5, and the final step in the process, is to optimize the virus for its hACE2 binding affinity (ability to infect humans) with experiments on live animals. This normally consists of infecting rodents, such as hACE2 transgenic mice (hACE2-mice), with the virus and extracting the highest viral load from 10 to 15 rounds of passage to obtain the strain with the optimal hACE2-binding affinity.
However, the authors of this report postulate that the Chinese scientists failed to use a "proper animal model" when testing the transmissibility of the virus. If they had, the scientists say the highly contentious nature of SARS-CoV-2 would have been obvious and the early claims of "not causing human-to-human transmission" would have not been made at the start of the pandemic.
The researchers suggest that "extensive laboratory-adaption" geared toward augmented transmissibility and lethality "may have driven the virus too far." The scientists believe that the virus might have lost the "capacity to [attenuate] both transmissibility and lethality during its current adaptation in the human population," as evidenced by the lack of attenuation by the virus despite its extensive spread globally and the emergence of a variant with "improved transmissibility."
https://www.taiwannews.com.tw/en/news/4009390
An international team of scientists will examine the possibility Sars-Cov-2 leaked from a laboratory as part of a comprehensive investigation into the origins of the virus.
The team is being set up as part of the Lancet COVID-19 Commission, a body established in July to “offer practical solutions” to the pandemic and make recommendations on how the next one can be avoided or better defended against.
The team looking at the origins of the virus will be led by Dr Peter Daszak, a British zoologist and leading authority on zoonotic spillover events.
Dr Daszak said yesterday he and his team would “systematically examine every theory” about the origin of the virus, carefully marshalling the scientific evidence for each. ...
No comments:
Post a Comment
Note: only a member of this blog may post a comment.